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Flea, Tick & Worming Treatment Comparison

Popular Brands and Their Effectiveness Against Fleas, Ticks and Worms

Keeping your dog or cat safe from fleas, ticks and worms should be one of the top priorities for any pet owner, but the number of brands on the market can often feel overwhelming.

Whether you are trying to decide between two particular medications, or perhaps finding an alternative to a treatment you’ve used before, an easy-to understand comparison can help you to choose.

The pages below will outline and compare the properties of each product such as: the parasites treated, the life stage treated, how the treatment is administered, the dosage schedule, active ingredients and how quickly the treatment starts working.

For a top-level comparison of the major brands, you might also like to read our Flea & Tick Treatment Comparison Chart the Heartworm Treatment Comparison Chart or the combined Flea, Tick & Worming Comparison.


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Activyl vs Advantage

Activyl vs Frontline

Activyl vs Revolution

Advantage vs Advantage II

Advantage vs Advantix

Advantage II vs Advantix II

Advantage Multi vs Advantage II

Bravecto vs Comfortis

Bravecto vs Frontline

Bravecto vs NexGard

Bravecto vs Trifexis

Capstar vs Comfortis

Credelio vs Bravecto

Credelio vs Comfortis

Credelio vs NexGard

Frontline Gold vs Frontline Plus

Frontline Plus vs Advantage II

Frontline vs Advantage

Frontline vs Advantix

Heartgard vs Heartgard Plus

Interceptor Plus vs Heartgard Plus

Interceptor vs Heartgard

Interceptor vs Interceptor Plus

K9 Advantix II vs Frontline Plus

NexGard vs Comfortis

NexGard vs Frontline

NexGard vs Trifexis

NexGard Spectra vs NexGard

PetArmor Plus vs Frontline Plus

Revolution vs Advantage

Revolution vs Advantage Multi

Revolution vs Frontline

Revolution vs Trifexis

Scalibor vs Seresto

Discontinued vs Trifexis

Sentinel vs Heartgard

Sentinel vs Interceptor

Sentinel vs Discontinued

Sentinel vs Trifexis

Simparica vs Bravecto

Simparica vs Comfortis

Simparica vs Frontline

Simparica vs NexGard

Trifexis vs Comfortis

Trifexis vs Heartgard

Tri-Heart Plus vs Heartgard

Vectra 3D vs Frontline

Comparing Flea & Tick Treatments for Dogs and Cats

Comparing Heartworm Treatments for Dogs and Cats

Comparing Flea, Tick & Worming Treatment for Dogs and Cats






Treatment Comparison

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Seresto Flea Collar for Large Dogs
$42.95
$48.40
Bravecto Chews For Dogs 44-88 lbs (20-40 kg)
$38.95
$50.80
Bravecto Chews For Dogs 9.9-22 lbs (4-10 kg)
$28.95
$46.00