What is Simparica for Dogs?

Simparica for dogs is a fast-acting treatment against ticks and fleas and their infestations. Administered as an easy once-a-month chewable tablet, Simparica provides continuous coverage for 35 days.Simparica maybe be used as an alternative to the product NexGard.

Once ingested, Simparica works quickly to kill fleas (Ctenocephalides felis) on your dog within 3 hours, providing rapid relief even for dogs with flea allergies. Simparica also controls and prevents flea infestations within the home by killing fleas before they can lay eggs.

As well as providing relief from fleas, Simparica chewables also treat and control various species of ticks including:

• Brown dog tick (Rhipicephalus sanguineus)
• Deer tick/Black legged tick (Ixodes scapularis)
• American dog tick (Dermacentorvariabilis)
• Lone star tick (Amblyommaamericanum)
• Gulf coast tick (Amblyommamaculatum)

Ticks can carry serious diseases that affect not only dogs, but humans as well. By killing ticks and tick infestations you can prevent the spread of potentially deadly tick-borne diseases.

Benefits

• Fast-acting – begins to kill fleas in just 3 hours
• Prevents and controls flea infestations within the home
• Comes in a tasty liver-flavored chew for easy administration
• 35-day coverage to allow for late dosing
• No more mess from topical preventatives

Which dogs are Simparica chewable tablets suitable for?

Simparica is recommended for dogs over 6 months of age, and with a body weight of 2.8 pounds (1.3kg) minimum.

Dosage Schedule

Simparica is designed as a once a month treatment, with dosage based on your dog’s weight.

Simparica chewable tablets can be offered by hand, broken up into food, or administered as per other medications. Care should be taken that the complete dose is consumed, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If a dose is missed, administer Simparica and resume a monthly dosing schedule.

Treatment for ticks and fleas with Simparica may begin at any time of the year.

What are the side effects of Simparica?

The most common side effects are vomiting and diarrhea. Lethargy has also been reported as an adverse reaction.

What precautions must be taken?

• Keep out of reach children and animals.
• Not for human use.
• Not for use on cats.
• Not for use on dogs under 6 months of age.
• The safe use of Simparica in breeding, pregnant or lactating dogs has not been evaluated.
• Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures.
• No known contraindications for the use of Simparicachewables.

How effective is Simparica (Sarolaner)?

In a well-controlled laboratory study, SIMPARICA began to kill fleas 3 hours after initial administration and reduced the number of live fleas by ≥96.2% within 8 hours after flea infestation through Day 35. In a separate well-controlled laboratory study, SIMPARICA demonstrated 100% effectiveness against adult fleas within 24 hours following treatment and maintained 100% effectiveness against weekly re-infestations for 35 days. In a study to explore flea egg production and viability, SIMPARICA killed fleas before they could lay eggs for 35 days. In a study to simulate a flea-infested home environment, with flea infestations established prior to the start of treatment and re-infestations on Days 7, 37 and 67, SIMPARICA administered monthly for three months demonstrated >95.6% reduction in adult fleas within 14 days after treatment and reached 100% on Day 60. In well-controlled laboratory studies, SIMPARICA demonstrated ≥99% effectiveness against an initial infestation of Amblyommaamericanum, Amblyommamaculatum, Dermacentorvariabilis, Ixodes scapularis, and Rhipicephalus sanguineus 48 hours post-administration and maintained >96% effectiveness 48 hours post re-infestation for 30 days. In a well-controlled 90-day US field study conducted in households with existing flea infestations of varying severity, the effectiveness of SIMPARICA against fleas on Day 30, 60 and 90 visits compared to baseline was 99.4%, 99.8%, and 100%, respectively. Dogs with signs of flea allergy dermatitis showed improvement in erythema, papules, scaling, alopecia, dermatitis/pyodermatitis and pruritus as a direct result of eliminating fleas.

Brand Comparison

• Simparica vs Bravecto
• Simparica vs Comfortis
• Simparica vs Frontline
• Simparica vs NexGard